Primary Myoglobinuria: Differentiate Myoglobinuria from Hemoglobinuria

[A case of paroxysmal nocturnal hemoglobinuria with elevation of serum creatine kinase activity and myoglobinuria].

Wake Forest University Case Conference ) Myoglobinuria , Hemoglobinuria , and Acute Renal Failure

Myoglobin and hemoglobin are often present in the urine of hospitalized patients. Differentiating between the two is difficult but important, and textbooks still may contain misconceptions regarding these two proteins. Here we discuss(a)the difficulties of detection, (b) how to differentiate myoglobinuria from hemoglobinuria, (c) the importance of such differentiation, (d) the etiology of acute...

Rhabdomyolysis and Other Causes of Myoglobinuria

Rhabdomyolysis can be defined as a clinical syndrome associated with the breakdown of skeletal muscle fibres and myocyte cell membranes, leading to release of muscle contents into the circulation, resulting in multiple complications, including hyperkalaemia. It is a medical emergency and can lead to cardiac arrest if not promptly treated. Myoglobinuria is an early feature of rhabdomyolysis, but...

Effects of perinatal asphyxia and myoglobinuria

Thirty four consecutive neonates with birth asphyxia or respiratory problems were examined in the first week of life to clarify the relation between neonatal myoglobinuria and acute renal failure. Investigations included determination of creatinine clearance, fractional sodium excretion, and N-acetyl-13-D glucosaminidase index as an indicator of tubular injury. The infants' gestational ages ran...

Myoglobinuria and renal failure in toluene poisoning.

Toluene (methylbenzene) is a colourless liquid used as a solvent in the manufacture of synthetic rubber paint and lacquer as well as trinitrotoluene (Fairhall, 1957). Chronic or acute exposure to high concentrations is known to be toxic and to cause renal and hepatocellular damage (O'Brien, Yeoman, and Hobby, 1971). This report deals with severe myoglobinuria and acute renal failure necessitati...